Halting pro-survival autophagy by TGFβ inhibition in bone marrow fibroblasts overcomes bortezomib resistance in multiple myeloma patients

Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury.

Changmeng Cui, Jianzhong Cui, Feng Jin et al. · PubMed · 2017 · 5.2K citations

Life Sciences, Neuroscience, Pharmacology +12

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark et al. · Journal of Biological Chemistry · 2007 · 4.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

Teru Hideshima, Paul G. Richardson, D Chauhan et al. · PubMed · 2001 · 1.5K citations

Medicine, Oncology, Pharmacology +17

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

Yukiko Kabeya, Noboru Mizushima, Akitsugu Yamamoto et al. · Journal of Cell Science · 2004 · 1.4K citations

Life Sciences, Biochemistry, Cell Biology +15

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

Per O. Seglen, Paul B. Gordon · Proceedings of the National Academy of Sciences · 1982 · 1.3K citations · Full text

Life Sciences, Biochemistry, Cell Biology +15