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Publication | Open Access

Nucleosomes and histones are present in glomerular deposits in human lupus nephritis

DOIFull Paper Access

140

Citations

2

References

1997

Year

Mieke van Bruggen, Cornelis Kramers, Birgitte Walgreen, Jd Elema, C. G. M. Kallenberg, J. van den Born, R J Smeenk, K.J.M. Assmann, S. Muller, Marc Monestier,
Nephrology Dialysis Transplantation

Abstract

Using polyclonal and monoclonal antihistone antisera, histones were identified in all patients with DPGN and their presence was associated with a decrease of HS staining. Nucleosomes were identified in five of 11 patients with DPGN and in two of six patients with MGN. This is the first demonstration of nucleosomes in glomerular deposits in SLE nephritis.

References

YearCitations

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