Predictors of Hemolytic Uremic Syndrome in Children During a Large Outbreak of<i>Escherichia coli</i>O157:H7 Infections

Abstract

Prospective studies are needed to further evaluate measures to prevent the progression of E coli O157:H7 infection to HUS and to assess further clinical and laboratory risk factors. These data argue against the use of antimotility agents in acute childhood diarrhea. Our finding that no intervention decreased HUS risk underscores the importance of preventing E coli O157:H7 infections.