Elastin fragmentation in atherosclerotic mice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death - Concepedia

Concepedia

Publication | Open Access

Elastin fragmentation in atherosclerotic mice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death

DOI Full Paper Access

195

Citations

16

References

2014

Year

Carole Van der Donckt, Jozef L. Van Herck, D. Schrijvers, Greetje Vanhoutte, Marleen Verhoye, Ines Blockx, Annemie Van der Linden, Dries Bauters, Henri Roger Lijnen, Judith C. Sluimer,

European Heart Journal

Abstract

Elastin fragmentation plays a key role in plaque destabilization and rupture. ApoE(-/-)Fbn1(C1039G+/-) mice represent a unique model of acute plaque rupture with human-like complications.

References

	Year	Citations

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