Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed

Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

Vesna Jevtović‐Todorović, Richard E. Hartman, Yukitoshi Izumi, +5

Journal of Neuroscience

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

Qing Guo, Bryce L. Sopher, Katsutoshi Furukawa, +4

PubMed

Intracellular Calcium LevelsTrophic Factor WithdrawalApoptosisCell DeathChromosome 14 +15

Alzheimer’s Presenilin Mutation Sensitizes Neural Cells to Apoptosis Induced by Trophic Factor Withdrawal and Amyloid β-Peptide: Involvement of Calcium and Oxyradicals

Qing Guo, Bryce L. Sopher, Katsutoshi Furukawa, +4

Journal of Neuroscience

Intracellular Calcium LevelsTrophic Factor WithdrawalCell DeathChromosome 14Social Sciences +16

Inhaled Anesthetic Enhancement of Amyloid-β Oligomerization and Cytotoxicity

Roderic G. Eckenhoff, Jonas Johansson, Huafeng Wei, +6

Anesthesiology

Alzheimerʼs PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide

Qing Guo, Katsutoshi Furukawa, Bryce L. Sopher, +5

Neuroreport

Presenilin-1 Mutations Increase Levels of Ryanodine Receptors and Calcium Release in PC12 Cells and Cortical Neurons

Sic L. Chan, Michael Mayne, Clark P. Holden, +2

Journal of Biological Chemistry

The Common Inhalation Anesthetic Isoflurane Induces Apoptosis and Increases Amyloid β Protein Levels

Zhongcong Xie, Yuanlin Dong, Uta Maeda, +4

Anesthesiology

The Inhalation Anesthetic Isoflurane Induces a Vicious Cycle of Apoptosis and Amyloid β-Protein Accumulation

Zhongcong Xie, Yuanlin Dong, Uta Maeda, +5

Journal of Neuroscience

Sevoflurane and Halothane Reduce Focal Ischemic Brain Damage in the Rat

David S. Warner, Claude McFarlane, Michael M. Todd, +2

Anesthesiology