Concepedia

The PD-1/B7-H1 Pathway Modulates the Natural Killer Cells versus Mouse Glioma Stem Cells

Bo Huang, Yi Ping Zhan, Wen Jing Zong, Chun Jiang Yu, Junfa Li, Yan Qu, Song Han

PLoS ONE · 2015 · 102 citations · 31 references

DOIFull text

Open access

Abstract

The results demonstrated that blockade of PD-1/B7H1 pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1-inhibited NK cells could be a feasible immune therapeutic approach against GBM.

References

31

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments

Brain Pathology · 2009 · 4K citations · Full text

PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

Stephen M. Ansell, Alexander M. Lesokhin, Ivan Borrello et al. · New England Journal of Medicine · 2014 · 3.5K citations · Full text