Bayesian models for screening and TB Mobile for target inference with Mycobacterium tuberculosis

A Diarylquinoline Drug Active on the ATP Synthase of <i>Mycobacterium tuberculosis</i>

Koen Andries, Peter Verhasselt, Jérôme Guillemont et al. · Science · 2004 · 2.2K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Statistical practice in high-throughput screening data analysis

Nathalie Malo, James A. Hanley, Sonia Cerquozzi et al. · Nature Biotechnology · 2006 · 726 citations

Natural Sciences, Bioinformatics, Biostatistics +12

SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis

Kapil Tahlan, Regina Wilson, David B. Kastrinsky et al. · Antimicrobial Agents and Chemotherapy · 2012 · 504 citations · Full text

Life Sciences, Microbiology, Molecular Biology +14

Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical Structure

Andreas Bender, Josef Scheiber, Meir Glick et al. · ChemMedChem · 2007 · 326 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Using Extended-Connectivity Fingerprints with Laplacian-Modified Bayesian Analysis in High-Throughput Screening Follow-Up

David Rogers, Robert D. Brown, Mathew Hahn · SLAS DISCOVERY · 2005 · 296 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16