Control of macromolecular synthesis in proliferating and resting syrian hamster cells in monolayer culture. II. Ribosome complement in resting and early G₁ Cells

Abstract

Abstract Using a new, sensitive and quantitative technique for determining the ribosomal‐RNA content of a measured number of cells, the cellular ribosome complement was compared for cultured hamster embryo cells in the stationary growth phase and in the early G 1 phase of the cell cycle. Cells from stationary phase cultures were found to contain less than 70% of the ribosome complement of the early G 1 phase cells, though the volumes of the two cell types were similar. This would imply that the stationary phase cell is physiologically different from a cell merely arrested at some point in the cell cycle.