Publication | Open Access
Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding
43
Citations
20
References
2006
Year
Chemokine BiologyMedicineMetalloproteinImmunologyReceptor (Biochemistry)Molecular BiologyCopper Macrocycle UnitSolid StateChemical ProbeNon-peptide LigandPharmacologyBiological Inorganic ChemistryAnti-cxcr4 Monoclonal AntibodiesDrug Discovery
The copper(II) complex of a novel rhodamine-azamacrocycle conjugate binds to the CXCR4 chemokine receptor and competes effectively against anti-CXCR4 monoclonal antibodies. The copper macrocycle unit adopts a trans-II configuration in the solid state.
| Year | Citations | |
|---|---|---|
Page 1
Page 1