Enzymatic Preparation of Enantiomerically Pure (1<i>R</i>,2<i>R</i>)- and (1<i>S</i>,2<i>S</i>)-2-Aminocyclohexanols

Abstract

Abstract The Pseudomonas cepacia lipase-catalyzed enantioselective hydrolysis of trans-2-(t-butoxycarbonyl)-aminocyclohexyl acetate was readily accomplished to provide a practical method for the industrial preparation of enantiomerically pure (1R,2R)- and (1S,2S)-2-aminocyclohexanols.