Selective cytotoxicity of squamocin on T24 bladder cancer cells at the S-phase via a Bax-, Bad-, and caspase-3-related pathways

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

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Medicine, Oncology, Pharmacology +9

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

Phang‐Lang Chen, Peter Scully, Jin‐Yuh Shew et al. · Cell · 1989 · 984 citations

Life Sciences, Cell Biology, Molecular Biology +16

BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo.

Shyng‐Shiou F. Yuan, Sou Ying Lee, Gang Chen et al. · PubMed · 1999 · 414 citations

Medicine, Molecular Biology, Oncology +17

Mitochondrial respiratory chain inhibitors induce apoptosis

Ernst J. Wolvetang, Karina L Johnson, Kenia G. Krauer et al. · FEBS Letters · 1994 · 404 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Natural substances (acetogenins) from the family <i>Annonaceae</i> are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I)

Mauro Degli Esposti, Anna Ghelli, Marina Ratta et al. · Biochemical Journal · 1994 · 240 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14