Studies of porphyrin biosynthesis by 13C-nuclear magnetic resonance; synthesis of [13C]porphobilinogen and its incorporation into protoporphyrin-IX

Abstract

[11-13C]Porphobilinogen is synthesised from [13C]methanol and is converted biochemically into [meso-13C]protoporphyrin-IX; assignments are made of signals in the 13C-n.m.r. spectra of protoporphyrin-IX and of other porphyrins.