Concepedia

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

Min Gao, Richard E. Nettles, Makonen Belema, Lawrence B. Snyder, Van N. Nguyen, Robert A. Fridell, Michael H. Serrano‐Wu, David R. Langley, Jin-Hua Sun, Donald R. O’Boyle,

Nature · 2010 · 937 citations · 11 references

DOIFull text

Open access

Concepts

References

11

Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

Volker Lohmann, Frank Körner, Jan Oliver Koch et al. · Science · 1999 · 2.8K citations

, , +16

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

Thomas Pietschmann, Artur Kaul, George Koutsoudakis et al. · Proceedings of the National Academy of Sciences · 2006 · 714 citations · Full text

, , +17

Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase

Timothy L. Tellinghuisen, Joseph Marcotrigiano, Charles M. Rice · Nature · 2005 · 476 citations · Full text

, , +16

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus

Robert A. Love, Oleg Brodsky, Michael J. Hickey et al. · Journal of Virology · 2009 · 233 citations · Full text

, , +17

Identification of Hepatitis C Virus NS5A Inhibitors

Julie A. Lemm, Donald R. O’Boyle, Mengping Liu et al. · Journal of Virology · 2009 · 194 citations · Full text

, , +17