Interferon-Lambda Genotype and Low Serum Low-Density Lipoprotein Cholesterol Levels in Patients With Chronic Hepatitis C Infection

Abstract

Our results suggest that low levels of LDL cholesterol in chronic hepatitis C patients may be a marker of host endogenous IFN response to hepatitis C and that subjects with the rs12979860 CC responder genotype may have a lower endogenous IFN response to the virus.