Concepedia

Quantification of Functional Selectivity at the Human α1A-Adrenoceptor

Bronwyn A. Evans, Natalie Broxton, Jon Merlin, Masaaki Sato, Dana S. Hutchinson, Arthur Christopoulos, Roger J. Summers

Molecular Pharmacology · 2010 · 73 citations · 33 references

DOI

Concepts

References

33

The 2.6 Angstrom Crystal Structure of a Human A <sub>2A</sub> Adenosine Receptor Bound to an Antagonist

Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson et al. · Science · 2008 · 1.8K citations · Full text

, , +17

GPCR Engineering Yields High-Resolution Structural Insights into β <sub>2</sub> -Adrenergic Receptor Function

Daniel M. Rosenbaum, Vadim Cherezov, Michael A. Hanson et al. · Science · 2007 · 1.3K citations

, , +17

Structure of a β1-adrenergic G-protein-coupled receptor

Tony Warne, María J. Serrano‐Vega, Jillian G. Baker et al. · Nature · 2008 · 1.3K citations · Full text

, , +12

Operational models of pharmacological agonism

J.W. Black, P. Leff · Proceedings of the Royal Society of London. Series B, Biological sciences · 1983 · 1.1K citations

, , +16

Crystal structure of opsin in its G-protein-interacting conformation

Patrick Scheerer, Jung Hee Park, Peter W. Hildebrand et al. · Nature · 2008 · 1K citations

, , +14