Comparison Between Adenoviral and Retroviral Vectors for the Transduction of the Thymidine Kinase PET Reporter Gene in Rat Mesenchymal Stem Cells

Véronique Roelants, Daniel Labar, Carole de Meester, Xavier Havaux, Antonio Tabilio, Sanjiv S. Gambhir, Mauro Di Ianni, Anne Bol, L Bertrand, Jean‐Louis Vanoverschelde

Journal of Nuclear Medicine · 2008 · 43 citations · 16 references

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Abstract

Our results demonstrate the feasibility of infecting MSCs with adenoviruses and retroviruses expressing the HSV1-tk PRG and suggest that infected MSCs can be noninvasively imaged with 18F-FHBG and small-animal PET after their transplantation into living animals.

References

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