Concepedia

ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft

Viraj J. Jasinghe, Zhigang Xie, Jianbiao Zhou, Jiaying Khng, Lai-Fong Poon, Senthilnathan Palaniyandi, Keith B. Glaser, Daniel H. Albert, Steven K. Davidsen, Chien-Shing Chen

Journal of Hepatology · 2008 · 34 citations · 42 references

DOI

Concepts

References

42

Estimates of the worldwide incidence of 25 major cancers in 1990

D. Maxwell Parkin, Paola Pisani, Jacques Ferlay · International Journal of Cancer · 1999 · 2.1K citations

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A mammalian protein targeted by G1-arresting rapamycin–receptor complex

Eric J. Brown, Mark W. Albers, Tae Bum Shin et al. · Nature · 1994 · 2.1K citations

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Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

Markus Guba, Philipp von Breitenbuch, Markus Steinbauer et al. · Nature Medicine · 2002 · 1.7K citations

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Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle.

Claude Vézina, ALICIA KUDELSKI, Suren N. Sehgal · The Journal of Antibiotics · 1975 · 1.7K citations · Full text

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Sorafenib Blocks the RAF/MEK/ERK Pathway, Inhibits Tumor Angiogenesis, and Induces Tumor Cell Apoptosis in Hepatocellular Carcinoma Model PLC/PRF/5

Li Liu, Yichen Cao, Charles Chen et al. · Cancer Research · 2006 · 1.5K citations · Full text

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