The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder

Lei Wang, Pinhua Li, Yicheng Zhang

Chemical Communications · 2004 · 102 citations · 18 references

Concepts

Abstract

The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder has been developed; terminal alkynes couple with aryl, alkenyl iodide and aryl bromide in the presence of cuprous iodide, triphenylphosphine, potassium hydroxide and ultrafine particle nickel(0) to provide the corresponding cross-coupling products with high yields.

References

18