High-Resolution In Vivo Imaging of the RPE Mosaic in Eyes with Retinal Disease

Abstract

For the first time, the mosaic of RPE cells has been directly visualized by AOSLO. Patients with hereditary retinal degenerations causing cone loss in the macula allowed visualization of RPE cells in areas where cones were missing. Regions with visible RPE cells demonstrated loss of visual function measured using microperimetry.