Restriction Enzyme Analysis of Ribosomal DNA Shows that <i>Candida inconspicua</i> Clinical Isolates Can Be Misidentified as <i>Candida norvegensis</i> with Traditional Diagnostic Procedures

Abstract

We identified 29 yeast isolates from 22 patients using the API ID32C panel. Twenty-eight of these isolates were Candida norvegensis and one was C. inconspicua. Although C. norvegensis is considered a pseudohypha-producing species, only one isolate produced pseudohyphae. Restriction enzyme analysis of PCR-amplified ribosomal DNA with four different enzymes proved that all isolates were C. inconspicua.