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Synthesis of 2′- and 3′-spiro-isoxazolidine derivatives of thymidine & their conversions to 2′,3′-dideoxy-2′,3′-didehydro-3′--substituted nucleosides by radical promoted fragmentation.

DerivativesEngineering3′-Spiro-isoxazolidine DerivativesOrganic ChemistryHeterocycle ChemistryPharmacologyDerivative (Chemistry)Synthetic ChemistryBiomolecular Engineering