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Active treatment of murine tumors with a highly attenuated vaccinia virus expressing the tumor associated antigen 5T4 (TroVax) is CD4+ T cell dependent and antibody mediated

Richard Harrop, Matthew G. Ryan, Kevin A. Myers, Irina Redchenko, Susan M. Kingsman, Miles W. Carroll

Cancer Immunology Immunotherapy · 2005 · 47 citations · 32 references

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References

32

Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin).

Sliwkowski Mx, Lofgren Ja, Lewis Gd et al. · PubMed · 1999 · 654 citations

, , +10

Nonreplicating vaccinia vector efficiently expresses recombinant genes.

Gerd Sutter, Bernard Moss · Proceedings of the National Academy of Sciences · 1992 · 605 citations

, , +17

Vaccination with a recombinant vaccinia virus encoding a “self” antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4 <sup>+</sup> T lymphocytes

Willem W. Overwijk, David Lee, Deborah R. Surman et al. · Proceedings of the National Academy of Sciences · 1999 · 382 citations

, , +17

Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3.

J. Gutheil, Tanya Campbell, Paul R. Pierce et al. · PubMed · 2000 · 370 citations

, , +17

Host Range and Cytopathogenicity of the Highly Attenuated MVA Strain of Vaccinia Virus: Propagation and Generation of Recombinant Viruses in a Nonhuman Mammalian Cell Line

Miles W. Carroll, Bernard Moss · Virology · 1997 · 330 citations

, , +15