The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos

Abstract

These data suggest that both the developmental arrest of a significant proportion of mosaic embryos on Day 4, and the cell death or reduced proliferation of aneuploid cells within an embryo may be responsible for the observed decrease of aneuploid blastomeres from compaction to the peri-implantation stage.