Atovaquone‐Statine “Double‐Drugs” with High Antiplasmodial Activity

Sergio Romeo, Silvia Parapini, Mario Dell’Agli, Nadia Vaiana, Pietro Magrone, Germana V. Galli, Anna Sparatore, Donatella Taramelli, Enrica Bosisio

ChemMedChem · 2007 · 17 citations · 11 references

Concepts

Abstract

Combining chemicals. Malaria is one of the most widespread parasitic infections in the world, however, the unavailability of a vaccine and the spread and intensification of drug resistance over the past 15–20 years have led to a dramatic decline in the efficacy of the most affordable antimalarial drugs. Herein, the development of “double-drugs” to tackle inhibition of P. falciparum growth is discussed.

References

11