The early programming of metabolic health: is epigenetic setting the missing link?

A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Timothy M. Frayling, Nicholas J. Timpson, Michael N. Weedon et al. · Science · 2007 · 4.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Variation in FTO contributes to childhood obesity and severe adult obesity

Christian Dina, Sophie Gallina, Emmanuelle Durand et al. · Nature Genetics · 2007 · 1.6K citations

Medicine, Pediatrics, Physiology +14

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Thomas Gerken, Christophe A. Girard, Yi‐Chun Loraine Tung et al. · Science · 2007 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

Epigenetic inheritance at the agouti locus in the mouse

Hugh D. Morgan, Heidi G. Sutherland, David I. K. Martin et al. · Nature Genetics · 1999 · 1.5K citations

Medicine, Genetics, Molecular Genetics +13

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

Xiaoqing Zhang, Guo Zhang, Hai Zhang et al. · Cell · 2008 · 1.3K citations · Full text

Life Sciences, Neurobiology, Physiology +16