Cardiac responses to <scp>β</scp>‐adrenoceptor stimulation is partly dependent on mitochondrial calcium uniporter activity

Abstract

Inhibition of the mitochondrial Ca(2+) uniporter decreases β-adrenoceptor response, uncoupling between workload and production of energetic metabolites. Our results support the hypothesis that the coupling of workload and energy supply is partly dependent on mitochondrial Ca(2+) uniporter activity.