Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration‐resistant prostate cancer

Abstract

The DNA/RNA gene outlier detection combined with siRNA cell proliferation assay identified FAM110B as a potential growth promoting key gene for CRPC. FAM110B appears to have a key role in the androgen signaling and progression of CRPC impacting multiple cancer hallmarks and therefore highlighting a potential therapeutic target.