<i>FZD4</i> as a Mediator of <i>ERG</i> Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

Santosh Gupta, Kristiina Iljin, Henri Sara, +7

Cancer Research

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

Sami Kilpinen, Reija Autio, Kalle Ojala, +16

Genome biology

High-Throughput Cell-Based Screening of 4910 Known Drugs and Drug-like Small Molecules Identifies Disulfiram as an Inhibitor of Prostate Cancer Cell Growth

Kristiina Iljin, Kirsi Ketola, Paula Vainio, +6

Clinical Cancer Research

Arachidonic Acid Pathway Members PLA2G7, HPGD, EPHX2, and CYP4F8 Identified as Putative Novel Therapeutic Targets in Prostate Cancer

Paula Vainio, Santosh Gupta, Kirsi Ketola, +11

American Journal Of Pathology

MedicineAnti-cancer AgentTumor SuppressorProstatic DiseaseCyp4f8 Identified +3

Monensin Is a Potent Inducer of Oxidative Stress and Inhibitor of Androgen Signaling Leading to Apoptosis in Prostate Cancer Cells

Kirsi Ketola, Paula Vainio, Vidal Fey, +2

Molecular Cancer Therapeutics

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins

Paula Vainio, Laura Lehtinen, Tuomas Mirtti, +10

Oncotarget

Chemoprevention StrategyAggressive Prostate CancerCancer BiologyTumor BiologySignaling Pathway +15

High-Throughput Transcriptomic and RNAi Analysis Identifies AIM1, ERGIC1, TMED3 and TPX2 as Potential Drug Targets in Prostate Cancer

Paula Vainio, John‐Patrick Mpindi, Pekka Kohonen, +6

PLoS ONE

Systems BiologyPotential Drug TargetsBiomarker TargetHigh-throughput TranscriptomicSirna Results +13

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration‐resistant prostate cancer

Paula Vainio, Maija Wolf, Henrik Edgren, +9

The Prostate

15‐Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial–mesenchymal transition, and promotes cell migration in cultured breast cancer cells

Laura Lehtinen, Paula Vainio, Harriet Wikman, +9

The Journal of Pathology

Tumor BiologyBreast OncologyOncologyMedicineHpgd Mrna +13

<i>PLA2G7</i> associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial‐mesenchymal transition in cultured breast cancer cells

Laura Lehtinen, Paula Vainio, Harriet Wikman, +8

The Journal of Pathology Clinical Research