Micellization versus Cyclodextrin–Surfactant Complexation

Abstract

Complete saturation of the complexation capacity of cyclodextrins (CDs) is not required for micellization to take place. Investigation of the competition between micellization and complexation of surfactant monomers with β-CD (shown schematically) shows the presence of a high concentration of uncomplexed β-CD in equilibrium with the micellar system. This concentration increases with the length of the hydrocarbon chain of the surfactant.