Concepedia

Catalyst-free tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles: facile synthesis of indole-3-substituted 3,4-dihydro(thio)coumarins

Zhuzhou Shao, Lubin Xu, Liang Wang, Hongtao Wei, Jian Xiao

Organic & Biomolecular Chemistry · 2014 · 49 citations · 29 references

DOI

Concepts

Abstract

The tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles has been developed and the biologically important indole-3-substituted dihydrocoumarins were obtained in good to excellent yields under catalyst-free conditions.

References

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