Concepedia

TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation

Shirin Bonni, Hongrui Wang, Carrie G. Causing, Peter A. Kavsak, Shannon L. Stroschein, Kunxin Luo, Jeffrey L. Wrana

Nature Cell Biology · 2001 · 310 citations · 29 references

DOI

Concepts

References

29

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn et al. · Nature · 1997 · 1.8K citations

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Controlling TGF-beta signaling.

Joan Massagué, Ye-Guang Chen · PubMed · 2000 · 1.8K citations

Controlling TGF-β signaling

Joan Massagué, Ye‐Guang Chen · Genes & Development · 2000 · 1.6K citations · Full text

The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling

Hidetoshi Hayashi, Shirin Abdollah, Yubin Qiu et al. · Cell · 1997 · 1.3K citations · Full text

, , +7

Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

Peter A. Kavsak, Richele K. Rasmussen, Carrie G. Causing et al. · Molecular Cell · 2000 · 1.3K citations · Full text

, , +12