Reproduction · 1978 · 27 citations · 3 references
Veterinary MedicineObstetricsPharmacologyReproductive MedicineReproductive PhysiologyBlastocyst DevelopmentEmbryo ImplantationHistamine ReleasePreimplantation Embryo DevelopmentRabbit ReproductionReproductive PharmacologyBirth Process In RabbitsEmbryonic ImplantationHistamine Release InhibitionHistamine Release SuppressionImplantation PhysiologyPharmacologic Histamine ReleaseRabbit Reproductive Pharmacology
When disodium cromoglycate, an inhibitor of histamine release, was instilled into the uterine lumen on Days 5 or 6 of pregnancy, the number of blastocysts implanting was significantly (P less than 0.002) reduced. Simultaneous instillation of histamine and disodium cromoglycate prevented the effect.
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