The<i>Ginkgo biloba</i>extract EGb 761^®and its main constituent flavonoids and ginkgolides increase extracellular dopamine levels in the rat prefrontal cortex

Abstract

The present results demonstrate that chronic but not acute treatment with EGb 761 increased dopaminergic transmission in the PFC. This finding may be one of the mechanisms underlying the reported effects of G. biloba in improving cognitive function.