Concepedia

The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability

Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber,

Drug Metabolism and Disposition · 2002 · 19 citations · 21 references

Concepts

PharmacyPharmacokineticsPharmacologyBioavailabilityClinical PharmacologyHepatic PharmacokineticsComparative PharmacokineticsDrug DispositionPharmacokinetics Across SpeciesSpecies Differences In Drug MetabolismDose-dependent Hepatic ExtractionHepatic Blood Flow LimitationOral Absorption KineticsOral Drug BioavailabilityPharmacokinetic ParametersRelative Oral Bioavailability

References

21

Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991

Robert J. Kuczmarski · JAMA · 1994 · 2.4K citations

Public Health, Nutrition, Public Health Nutrition +10

Increasing Prevalence of Overweight Among US Adults

Robert J. Kuczmarski · JAMA · 1994 · 1.6K citations

Public Health, Population Health Sciences, Public Health Nutrition +6

Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs

Jonathan R.S. Arch, A. T. Ainsworth, Michael A. Cawthorne et al. · Nature · 1984 · 730 citations

Life Sciences, Endocrinology, Pharmacology +16

Obesity: How Big a Problem?

Ingrid Wickelgren · Science · 1998 · 202 citations

Agriculture, Chronic Disease Prevention, Nutrition +14

Human β3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides

Linda Brockunier, Emma R. Parmee, Hyun Ok et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 199 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6