Concepedia

Simple and Efficient One-Pot Synthesis of 2-Substituted Benzoxazole and Benzothiazole

Sachin S. Patil, Vivek D. Bobade

Synthetic Communications · 2009 · 41 citations · 16 references

DOI

Concepts

Abstract

2-Substituted benzoxazole and benzothiazole were synthesized from condensation of aldehyde and 2-aminophenol or 2-aminothiophenol via a one-pot process using diethyl bromo phoshonate and tert-butyl hypochlorite.

References

16

Copper-Catalyzed Domino Annulation Approaches to the Synthesis of Benzoxazoles under Microwave-Accelerated and Conventional Thermal Conditions

Russell D. Viirre, Ghotas Evindar, Robert A. Batey · The Journal of Organic Chemistry · 2008 · 253 citations

, , +13

Antitumor Benzothiazoles. 8. Synthesis, Metabolic Formation, and Biological Properties of the <i>C</i>- and <i>N</i>-Oxidation Products of Antitumor 2-(4-Aminophenyl)benzothiazoles

Eiji Kashiyama, Ian Hutchinson, Mei‐Sze Chua et al. · Journal of Medicinal Chemistry · 1999 · 228 citations

, , +13

626. The preparation of benziminazoles and benzoxazoles from Schiff's bases. Part I

F. F. Stephens, J. D. Bower · Journal of the Chemical Society (Resumed) · 1949 · 181 citations

, , +4

UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.

M. Ueki, Keiichi Ueno, Shinji Miyadoh et al. · The Journal of Antibiotics · 1993 · 123 citations · Full text

, , +15

Oxidative cyclization of thiophenolic and phenolic Schiff's bases promoted by PCC: a new oxidant for 2-substituted benzothiazoles and benzoxazoles

Chandrasekar Praveen, K. Hemanth Kumar, D. Muralidharan et al. · Tetrahedron · 2008 · 120 citations

, , +9