Archives of Disease in Childhood · 2010 · 87 citations · 9 references
Public HealthChild HealthPediatricsClinical EpidemiologyPediatric EpidemiologyPharmacovigilancePediatric SafetyPharmacoepidemiologyAlternative MedicineComplementary MedicinePediatric Adverse Reaction MonitoringSerious Adverse Events
OBJECTIVE: To determine the types of adverse events associated with the use of complementary and alternative medicine (CAM) that come to the attention of Australian paediatricians. DESIGN: Monthly active surveillance study of CAM-associated adverse events as reported to the Australian Paediatric Surveillance Unit between January 2001 and December 2003. RESULTS: There were 39 reports of adverse events associated with CAM use, including four reported deaths. Reports highlighted several areas of concern, including the risks associated with failure to use conventional medicine, the risks related to medication changes made by CAM practitioners and the significant dangers of dietary restriction. The reported deaths were associated with a failure to use conventional medicine in favour of a CAM therapy. CONCLUSION: CAM use has the potential to cause significant morbidity and fatal adverse outcomes. The diversity of CAM therapies and their associated adverse events demonstrate the difficulty addressing this area and the importance of establishing mechanisms by which adverse effects may be reported or monitored.
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Joanne Barnes, Simon Mills, Neil C Abbot et al. · British Journal of Clinical Pharmacology · 1998 · 259 citations · Full text
Attitudinal survey of voluntary reporting of adverse drug reactions
Eland, Belton, van Adrianus Grootheest et al. · British Journal of Clinical Pharmacology · 1999 · 258 citations · Full text
Nigel W. Crawford, Domenic R. Cincotta, Alissa Lim et al. · BMC Complementary and Alternative Medicine · 2006 · 121 citations · Full text