Prospective first-trimester screening for trisomy 21 in 30,564 pregnancies

Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy.

K. H. Nicolaides, G.B. Azar, Dominic Byrne et al. · BMJ · 1992 · 1K citations · Full text

RANDOMISED CONTROLLED TRIAL OF GENETIC AMNIOCENTESIS IN 4606 LOW-RISK WOMEN

Ann Tabor, Mette Madsen, Erikb. Obel et al. · The Lancet · 1986 · 871 citations

Fertility, Prenatal Genetic Testing, Low-risk Women +10

First and second trimester antenatal screening for Down's syndrome: the results of the Serum, Urine and Ultrasound Screening Study (SURUSS)

Nicholas Wald, Charles H. Rodeck, Allan Hackshaw et al. · Health Technology Assessment · 2003 · 584 citations · Full text

Obstetric Imaging, Diagnosis, Gynecology +21

A screening program for trisomy 21 at 10–14 weeks using fetal nuchal translucency, maternal serum free β‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A

Kevin Spencer, Vivienne Souter, Natasha Tul et al. · Ultrasound in Obstetrics and Gynecology · 1999 · 570 citations

Integrated Screening for Down's Syndrome Based on Tests Performed during the First and Second Trimesters

Nicholas Wald, Hilary Watt, Allan Hackshaw · New England Journal of Medicine · 1999 · 537 citations · Full text