Comparison of Segmentation-Based Attenuation Correction Methods for PET/MRI: Evaluation of Bone and Liver Standardized Uptake Value with Oncologic PET/CT Data

Abstract

Without bone segmentation, the SUVs of spine lesions were considerably underestimated; however, the bias was acceptable with bone segmentation. In liver lesions, the segmentation-based AC methods yielded a negative bias in SUV; however, inclusion of the bone and fat segments reduced the SUV bias. The results of this study will be useful for understanding organ-dependent bias in SUV between PET/CT and PET/MRI.