Publication | Closed Access
Polyethylenimine‐Grafted Multiwalled Carbon Nanotubes for Secure Noncovalent Immobilization and Efficient Delivery of DNA
375
Citations
37
References
2005
Year
EngineeringGene DeliveryBiomedical EngineeringEfficient DeliveryElectrostatic InteractionsNanomedicineDna NanotechnologyDna ComputingCarbon NanotubesPolymer ChemistryNanobiotechnologyDna ReplicationDna DeliveryMultiwalled Carbon NanotubesPolymer-drug ConjugateDrug Delivery SystemsNano-drug DeliveryMedicineSecure Noncovalent Immobilization
DNA hits the wall: DNA is immobilized securely onto the surface of multiwalled carbon nanotubes through electrostatic interactions with grafted polyethylenimine (PEI; see picture). The polyethylenimine-graft multiwalled carbon nanotubes carrying DNA show transfection efficiency for DNA delivery similar to or even several times higher than PEI.
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