A Novel Approach to Predict the Likelihood of Specific Ovarian Tumor Pathology Based on Serum CA-125: A Multicenter Observational Study

Ben Van Calster, L. Valentin, Caroline Van Holsbeke, Jing Zhang, D. Jurkovic, Andrea Alberto Lissoni, A. C. Testa, Artur Czekierdowski, D. Fischerová, Ekaterini Domali,

Cancer Epidemiology Biomarkers & Prevention · 2011 · 39 citations · 27 references

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Abstract

Our results confirm the limited clinical value of CA-125 for preoperative discrimination between benign and malignant ovarian pathology. We have shown that CA-125 may be used in a different way. By using likelihood reference tables, we believe clinicians will be better able to interpret preoperative serum CA-125 results in patients with adnexal masses.

References

27