6-Mercaptopurine influences <i>TPMT</i> gene Transcription in a <i>TPMT</i> Gene Promoter Variable Number of Tandem Repeats-Dependent Manner

Abstract

These data suggest that the TPMT gene promoter VNTR architecture can be potentially used as a pharmacogenomic marker to predict toxicity due to 6-MP treatment in acute lymphoblastic leukemia patients.