Protein adsorption to polyethylene glycol modified liposomes from fibrinogen solution and from plasma

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.

Demetrios Papahadjopoulos, Theresa M. Allen, Alberto Gabizón et al. · Proceedings of the National Academy of Sciences · 1991 · 1.6K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

Theresa M. Allen, Cecilie Cetti Hansen, Francisco J. Plaza Martín et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 1.4K citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Protein adsorption to poly(ethylene oxide) surfaces

Wayne R. Gombotz, Guanghui Wang, Thomas A. Horbett et al. · Journal of Biomedical Materials Research · 1991 · 630 citations

Natural Sciences, Materials Engineering, Materials Science +17

Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: Studies with poly(ethylene glycol)-coated vesicles

Judith Senior, Cristina Delgado, Derek Fisher et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 521 citations

Life Sciences, Biophysics, Pharmacokinetics +16

Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target

A.L. Klibanov, Kazuo Maruyama, Anne Marie Beckerleg et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 483 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17