Asymmetric transfer hydrogenation of ketones and imines with novel water-soluble chiral diamine as ligand in neat water

Abstract

A novel water-soluble rhodium(III)catalyst prepared from o,o′-aminated N-tosyl-1,2-diphenylethylenediamine(S,S)-3 and [Cp*RhCl2]2, which was efficient for the asymmetric transfer hydrogenation of ketones and imines in neat water with high reactivity and excellent enantioselectivity, has been developed.