Combinations of Polymorphisms in Genes Involved in the 5-Fluorouracil Metabolism Pathway Are Associated with Gastrointestinal Toxicity in Chemotherapy-Treated Colorectal Cancer Patients - Concepedia

Concepedia

Publication | Closed Access

Combinations of Polymorphisms in Genes Involved in the 5-Fluorouracil Metabolism Pathway Are Associated with Gastrointestinal Toxicity in Chemotherapy-Treated Colorectal Cancer Patients

52

Citations

34

References

2011

Year

Shoaib Afzal, Milena Gusella, Ben Vainer, Ulla Vogel, Jón Trærup Andersen, Kasper Broedbaek, Morten Aagaard Petersen, Espen Jimenez‐Solem, Laura Bertolaso, Carmen Barile,

Clinical Cancer Research

Abstract

Our results indicate that MTHFR activity and a specific combination of the MTHFR 1298A>C and TYMS 3'-UTR ins/del polymorphisms are possible predictors of 5-FU treatment-related toxicity.

References

	Year	Citations

Page 1