Tris (Dibenzylideneacetone) Dipalladium, a<i>N</i>-Myristoyltransferase-1 Inhibitor, Is Effective against Melanoma Growth<i>In vitro</i>and<i>In vivo</i>

Abstract

Tris DBA is thus a novel inhibitor of N-myristoyltransferase-1 with significant antitumor activity and is well tolerated in vivo. Further preclinical evaluation of Tris DBA and related complexes is warranted.