Cephalosol: An Antimicrobial Metabolite with an Unprecedented Skeleton from Endophytic <i>Cephalosporium acremonium</i> IFB‐E007

Abstract

Cephalosol (1), a potent antimicrobial secondary metabolite with a new carbon skeleton, was characterized from the culture of Cephalosporium acremonium IFB-E007 that used to reside as an endophyte in Trachelospermum jasminoides (Apocynaceae). Its structure and absolute configuration were unambiguously determined by spectroscopic and computational approaches.