Concepedia

Publication | Open Access

Monoclonal Antibody against Cell Surface GRP78 as a Novel Agent in Suppressing PI3K/AKT Signaling, Tumor Growth, and Metastasis

DOIFull Paper Access

179

Citations

26

References

2013

Year

Ren Liu, Xiu‐Qing Li, Wenming Gao, Yue Zhou, Shiuan Wey, Satyajit K. Mitra, Valery Krasnoperov, Dezheng Dong, Dan Li, Genyuan Zhu,
Clinical Cancer Research

Abstract

GRP78-specific antibody MAb159 modulates the PI3K pathway and inhibits tumor growth and metastasis. Humanized MAb159 will enter human trials shortly.

References

YearCitations

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