Concepedia

RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia

A Carbia-Nagashima, Juan Gerez, Carolina Perez-Castro, Marcelo Páez-Pereda, Susana Silberstein, Günter K. Stalla, Eduardo Arzt

Cell · 2007 · 307 citations · 45 references

DOIFull text

Open access

Concepts

References

45

Regulation of hypoxia-inducible factor 1α is mediated by an O <sub>2</sub> -dependent degradation domain via the ubiquitin-proteasome pathway

Eric Huang, Jie Gu, Maureen Schau et al. · Proceedings of the National Academy of Sciences · 1998 · 2.1K citations · Full text

, , +15

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

Gregg L. Semenza, Bing‐Hua Jiang, Sandra W. Leung et al. · Journal of Biological Chemistry · 1996 · 1.8K citations · Full text

, , +15

SUMO-1 Modification of IκBα Inhibits NF-κB Activation

Joana Desterro, Manuel S. Rodríguez, Ronald T. Hay · Molecular Cell · 1998 · 1K citations

, , +12

Functional Heterogeneity of Small Ubiquitin-related Protein Modifiers SUMO-1 versus SUMO-2/3

Hisato Saitoh, Joseph Hinchey · Journal of Biological Chemistry · 2000 · 875 citations · Full text

, , +9

Polymeric Chains of SUMO-2 and SUMO-3 Are Conjugated to Protein Substrates by SAE1/SAE2 and Ubc9

Michael H. Tatham, Ellis Jaffray, O. Anthony Vaughan et al. · Journal of Biological Chemistry · 2001 · 807 citations · Full text

, , +11