Journal of Micromechanics and Microengineering · 2007 · 75 citations · 16 references
EngineeringBioengineeringBiomedical EngineeringFluid DynamicsMicroelectromechanical SystemsMicrofabricationMicrofluidic Device FabricationMicrofluidic DevicesMicrofluidic SystemsMicrofluidic TransportMicrofluidicsCapillary FlowCapillary Flow ControlMicrochannel DesignMicrochannel FabricationMicrochannel HydrodynamicsMicrofluidic Device DesignMicrofluidic FlowMicrofluidic Flow Control
This note presents a simple method to control the speed of the autonomous capillary flow using an array of hydrophobic patterns. The microfluidic system in this note was composed of two planar parallel plates that were separated by spacers. The bottom plate had a hydrophilic microchannel which was surrounded by hydrophobic tracks. The top surface was relatively hydrophobic compared to the bottom plate. These hydrophobic tracks and the hydrophobic patterns in the middle of the microchannels were patterned using PDMS stamps by contact printing. By controlling the ratio of hydrophobic area to the whole channel width and the distance between two plates, it was possible to control the capillary flow speed at specific positions. Using this method, it is expected to achieve a sufficient incubation time for biological reactions in microfluidic devices using the capillary flow.
16
Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography
Marc Unger, Hou-Pu Chou, Todd Thorsen et al. · Science · 2000 · 4K citations
Surface-Directed Liquid Flow Inside Microchannels
Bin Zhao, Jeffrey S. Moore, David J. Beebe · Science · 2001 · 763 citations
Autonomous Microfluidic Capillary System
David Juncker, Heinz Schmid, Ute Drechsler et al. · Analytical Chemistry · 2002 · 427 citations
Design of a Compact Disk-like Microfluidic Platform for Enzyme-Linked Immunosorbent Assay
Siyi Lai, Shengnian Wang, Jun Luo et al. · Analytical Chemistry · 2004 · 423 citations