Concepedia

Publication | Open Access

Polycomb Repressive Complex 2 Regulates Normal Development of the Mouse Heart

DOIFull Paper Access

209

Citations

33

References

2011

Year

Aibin He, Qing Ma, Jingjing Cao, Alexander von Gise, Pingzhu Zhou, Huafeng Xie, Bing Zhang, Michael Hsing, Danos C. Christodoulou, Patrick Cahan,
Circulation Research

Abstract

Our study reveals a previously undescribed role of EZH2 in regulating heart formation and shows that perturbation of the epigenetic landscape early in cardiogenesis has sustained disruptive effects at later developmental stages.

References

YearCitations

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